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Adolescent male chimps in large community strive to be alphas

Written By Unknown on Kamis, 20 September 2012 | 07.35

ScienceDaily (Sep. 19, 2012) — An Ohio University anthropologist reports the first observation of dominance relationships among adolescent male chimpanzees, which he attributes to the composition of their community. Hogan Sherrow spent eight years studying the Ngogo community of chimpanzees in Kibale National Park in western Uganda. Ngogo is the biggest chimpanzee community on record, with more than 150 members and about twice as many males as found in other chimp communities across Africa.

Unlike their adult male counterparts, which have a well-documented dominance hierarchy, adolescent males have not been known to establish dominance relationships. During four field seasons between 2000 and 2004, however, Sherrow found that some adolescent males pant grunted to other adolescent males on a consistent basis. Research by Jane Goodall established that pant grunts are made by subordinate individuals to dominant ones, Sherrow explained.

"It calms hostilities. It means, 'I know that you're stronger than me, so don't beat me up.' It's like they're sending up the white flag," said Sherrow, an assistant professor of anthropology who published his recent findings in the journal Folia Primatologica.

After ranking the 17 adolescent males in order of dominance, Sherrow concluded that the biggest and oldest animals were at the top of the hierarchy. There were only two exceptions, males that appeared to act in a subordinate manner due to physical injuries.

Sherrow suggests that he observed dominance relationships in the adolescent males of this chimpanzee community due to its size and heightened competition for females. Each male in Ngogo must contend with 35 to 40 others, whereas most communities contain 10 to 15 competitors for mating. Adolescent male chimps also may vie for access to high-ranking adult males as a competitive strategy.

Adult male chimpanzees have clear and defined dominance relationships that depend on size, strength and the ability to form alliances in the community. The most dominant males have priority access to resources and potential mates and usually father more offspring.

"We should not be surprised that adolescent males can form these dominance relationships. Adults males form them, and adolescent males need to learn them at some point," Sherrow said.

Studies of other immature males in primate, mammal and even human communities with intense competition for resources also have found adolescent dominance hierarchies, he added.

Because the Ngogo community is unusually large, Sherrow noted that scientists should seek to observe this behavior in another neighboring community of this size to determine if a similar hierarchy can be documented. The Ngogo study site, located in the Ugandan rain forest, was established in 1995 and has been observed daily by researchers.

The recent study not only offers a new view of chimpanzee behavior, but could shed light on human power and dominance as well, Sherrow suggested.

"Because chimpanzees, along with bonobos, are our closest living relatives, understanding things like how and why they form dominance relationships helps us understand the drive for status and prestige in humans," he said.

The L.S.B. Leakey Foundation, the American Society of Primatologists, the Sigma Xi Foundation, the John F. Enders Foundation and Yale University provided support for the research.

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Journal Reference:

  1. Hogan M. Sherrow. Adolescent Male Chimpanzees at Ngogo, Kibale National Park, Uganda, Have Decided Dominance Relationships. Folia Primatologica, 2012; 83 (2): 67 DOI: 10.1159/000341168

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20 Sep, 2012


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Antibiotic use aids MRSA spread in hospital and infection control measures do little to prevent it, says hospital study

ScienceDaily (Sep. 20, 2012) — The use of a commonly prescribed antibiotic is a major contributor to the spread of infection in hospitals by the 'superbug' MRSA, according to new research. The study also found that increasing measures to prevent infection -- such as improved hygiene and hand washing -- appeared to have only a small effect on reducing MRSA infection rates during the period studied.

MRSA -- methicillin-resistant Staphylococcus aureus -- is a bacteria that causes hospital-acquired infection and is resistant to all of the penicillin-type antibiotics frequently used in hospitals to prevent and treat infection. It can cause serious infections of the skin, blood, lungs and bones.

The researchers -- led by St George's, University of London -- tracked MRSA infection over 10 years from 1999 to 2009 at St George's Hospital, looking at how it has adapted to survive in a hospital environment and at factors that affected its prevalence. They found that a significant drop in MRSA rates coincided with a reduction in hospital prescriptions of ciprofloxacin, the most commonly prescribed antibiotic of the fluoroquinolone family.

Over a short period of the study, ciprofloxacin prescriptions fell from 70-100 daily doses for every thousand occupied beds to about 30 doses. In the same period, the number of patients identified by the laboratory to be infected with MRSA fell by half, from an average of about 120 a month to about 60. Following this, over the last two years of the study both the drug prescription level and MRSA rates remained at these reduced levels. Symptoms of MRSA infection can range from very mild to severe, but it is not known how many of the cases examined in the study were serious.

The study -- published in the Journal of Antimicrobial Chemotherapy -- looked at whether other factors such as improved infection control measures may have contributed to this decrease in infection. However, during a four-year period when more stringent infection control policies were introduced -- including improved cleaning and hand washing, and screening patients for MRSA on arrival at hospital -- the only major reduction in MRSA infection rates coincided with the reduction in ciprofloxacin prescriptions.

Lead author Dr Jodi Lindsay, a reader in microbial pathogenesis at St George's, University of London, said: "Surprisingly, it wasn't hygiene and hand washing that were the main factors responsible for the decrease in MRSA in the hospital. Rather, it seemed to be a change in the use of a particular group of antibiotics. Hand washing and infection control are important, but they were not enough to cause the decrease in MRSA we saw."

Dr Lindsay said the study suggested that MRSA relies on ciprofloxacin -- and fluoroquinolones in general -- to thrive in hospitals, as well as penicillin-type drugs, which was already assumed. The fluoroquinolone group of antibiotics have a similar enough mechanism of action to assume that the effect would be the same for them all.

She added that the findings suggest the most effective way to control MRSA and other hospital-based superbugs is to continue finding alternative ways to use antibiotics, rather than simply focusing on infection control techniques.

As well as identifying factors that influenced prevalence, the researchers identified the strain of MRSA that has become dominant. This strain -- CC22 -- has thrived by developing and maintaining multi-drug resistance, and becoming more fit to survive on hospital surfaces than other strains.

Dr Tim Planche, consultant microbiologist at St George's Healthcare NHS Trust and one of the co-authors of the study, said: "The Trust currently has infection rates among the lowest in London, having successfully driven acquisitions down over the past five or six years using a combination of both tough hygiene regimes and careful selective use of antibiotics. These findings, however, provide valuable insight and certainly warrant further investigation, which could lead to the development of even more effective infection control strategies in future."

Dr Lindsay said that studying the dynamic of how MRSA bacteria strains continue to evolve in hospitals in response to changing practice and interventions, such as infection control and antibiotic prescribing, will be essential to determine which interventions work, which are cost effective, and which are likely to have the best long-term outcomes.

She added: "But it seems that we now have an excellent opportunity to control superbugs in hospitals by re-examining how we prescribe antibiotics and ensuring we're using them in the most effective way possible."

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The above story is reprinted from materials provided by University of St George's London.

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Journal Reference:

  1. G. M. Knight, E. L. Budd, L. Whitney, A. Thornley, H. Al-Ghusein, T. Planche, J. A. Lindsay. Shift in dominant hospital-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) clones over time. Journal of Antimicrobial Chemotherapy, 2012; 67 (10): 2514 DOI: 10.1093/jac/dks245

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Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

20 Sep, 2012


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Landing pads being designed for extraterrestrial missions

ScienceDaily (Sep. 20, 2012) — When the Mars Science Laboratory's Curiosity rover landed on Aug. 6, it was another step forward in the effort to eventually send humans to the Red Planet. Using the lessons of the Apollo era and robotic missions to Mars, NASA scientists and engineers are studying the challenges and hazards involved in any extraterrestrial landing.

The technology is known as "vertical takeoff-vertical landing." According to a group working in NASA's Engineering and Technology Directorate at the Kennedy Space Center in Florida, the best approach requires a landing pad already be in place.

"One of the greatest challenges to Apollo astronauts landing on the moon was dust, rocks and debris obscuring their vision during the final part of the descent," said Rob Mueller, a senior technologist in Kennedy's Surface Systems Office and Lunar Destination co-lead for NASA's Human Spaceflight Architecture Team. "When the Apollo lunar modules reached the 30-meter point (about 100 feet), the dust was like a fog making it difficult to see their landing site. Similarly, photographs show there were some rocks and dust kicked up by the rocket engines on the sky-crane lowering the Curiosity lander onto the Martian surface."

As the Mars Science Laboratory's descent stage used rocket engines to hover, its sky crane lowered the Curiosity rover with a 25-foot tether to a soft landing on the surface.

Mueller and others are working on ways to develop landing pads that could be robotically constructed in advance of future human expeditions to destinations such as the moon or Mars. These specially constructed landing sites could greatly reduce the potential for blowing debris and improve safety for astronauts who make the trip to Mars or another destination.

"Our best estimates indicate that descent engines of the Apollo landers were ejecting up to one-and-a-half tons of rocks and soil," said Dr. Phil Metzger, a research physicist in Kennedy's Granular Mechanics and Regolith Operations Laboratory. "It will be even more challenging when we land humans on Mars. The rocket exhaust will dig a deep hole under the lander and fluidize the soil. We don't know any way to make this safe without landing pads."

Building a landing site in advance of human arrival is part of the plan.

"Robotic landers would go to a location on Mars and excavate a site, clearing rocks, leveling and grading an area and then stabilizing the regolith to withstand impact forces of the rocket plume," Mueller said. "Another option is to excavate down to bedrock to give a firm foundation. Fabric or other geo-textile material could also be used to stabilize the soil and ensure there is a good landing site."

Metzger explained that one of the ways to ensure an on-target landing would be to have robotic rovers place homing beacons around the site.

"Tracking and homing beacons would help a spacecraft reach the specific spot where the landing pad had been constructed," he said.

Landing pad technology may be perfected on Earth well in advance of its use elsewhere in the solar system.

"Several commercial space companies are already discussing returning rocket stages to Kennedy or Cape Canaveral saving on the cost of sending payloads to low Earth orbit," Mueller said. "Rather than the first stage simply falling into the ocean, the rocket would land vertically back here at the Cape to be reused."

While landing pads will provide a smooth touchdown location, they will also require advanced technology design and decisions on how large the landing pad should be.

"One of the factors we have to consider is the atmosphere where a landing will take place," Metzger said. "The Earth has a dense atmosphere that focuses the rocket exhaust onto the ground, but also reduces how far the ejected material is dispersed. Mars, on the other hand, has an atmospheric density that is 1 percent that of Earth. It still focuses the plume into a narrow jet that digs into the soil, but it provides less drag so the ejected soil will actually travel farther.

"Then compare that to the moon with no atmosphere," he said. "The plume won't be focused so it won't dig a deep hole in the soil, but the ejected material will travel vast distances at high velocity. It is like a sandblaster on steroids. So the requirements for a landing pad are determined by the destination we're landing on."

Metzger envisions circular landing pads from about 50 to 100 meters (about 165 to 330 feet) in diameter.

"The specialized material taking the heat of the engine plume would be in the middle," he said. "The area surrounding the center would be designed to hold up support equipment."

Another issue is what substances to use in building the landing pads.

"Tests with prototype landers show that while pads are safer than touching down on natural surfaces, certain pad materials can produce debris of their own," Metzger said. "A supersonic rocket exhaust becomes extremely hot when it impacts a surface. Asphalt or concrete are out of the question because the temperature causes those materials to break apart, throwing chunks of material in all directions."

During investigations of prototype landers, various materials have been examined on the pads from which the vehicles have vertically taken off and landed.

"We've tested several types of materials and it seems that basalt regolith mixed with polymer binders hold up well," Metzger said.

However, the one substance for landing pads that shows the most promise is the material used on spacecraft heat shields.

"Of all the substances we studied, ablative materials seem to work best," Metzger said.

Ablative substances were used on the heat shields for spacecraft during Mercury, Gemini and Apollo. The heat of re-entry was dissipated by burning off successive layers.

"While ablative materials seem to work well, the layers will eventually all burn away," Mueller said. "So next we may try reusable thermal protection material similar to that used on the space shuttle tiles or the Orion capsules."

A human expedition to Mars is still many years away, but Mueller says now is the time to start planning for how to land on another planet.

"The technology we envision will take 10 to 15 years to develop," he said. "We need to begin verifying that these concepts will work, and that's why we are already involved in the research."

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20 Sep, 2012


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Sudden cardiac death is associated with a thin placenta at birth, researchers find

ScienceDaily (Sep. 19, 2012) — Researchers studying the origins of sudden cardiac death have found that in both men and women a thin placenta at birth was associated with sudden cardiac death. A thin placenta may result in a reduced flow of nutrients from the mother to the fetus. The authors suggest that sudden cardiac death may be initiated by impaired development of the autonomic nervous system in the womb, as a result of fetal malnutrition.

The new study, published today in the International Journal of Epidemiology, also found that sudden death was associated independently with poor educational attainment. However, sudden cardiac death was not associated with maternal body size, fetal size at birth, or the length of gestation.

Professor David Barker and colleagues examined sudden death within the Helsinki Birth Cohort, which consists of 6075 men and 6370 women who were born in the city during 1934-1944 and attended child welfare clinics. Detailed information was recorded on the birth records of the group including the placental weight and the length and breadth of the placental surface as well as the child's weight, head circumference, and length.

Professor Barker, of the University of Southampton, comments that 'There is currently a growing body of research that shows that coronary heart disease is associated with alterations in prenatal growth and this has led to the hypothesis that coronary heart disease originates in the womb as a consequence of fetal malnutrition. In research recently carried out by myself and colleagues, we found that coronary heart disease among men was associated with altered shape and size of the placenta.'

'Our new research published today continues the investigation of the relationship between cardiac death and development within the womb. Our new findings suggest that sudden death may be initiated by the impaired development of the autonomic nervous system in the womb, due to placental thinness. A thin placenta may result in fetal malnutrition, due to a shallow invasion of the spiral arteries in the placenta which provide nutrients and blood to the baby. There is evidence that people who experience fetal malnutrition and who are small at birth have an increased sympopathoadrenal response to acute stress, which is known to be linked to death from cardiac arrest.'

Among women, sudden death was associated with a large placental area in comparison to the baby's weight. Placenta expansion in sheep is well documented and the findings in this study suggest that the placenta attempted to compensate for a thin surface by expanding the area of the surface. Professor Barker notes that 'there is evidence that compensatory placental expansion occurs in human and that this expansion may be beneficial in some circumstances. However, if the compensation is inadequate and the fetus continues to be under nourished then the need to share its nutrients with an enlarged placenta may become a metabolic burden and the quality of fetal development may be harmed. We believe that the female foetuses in our study compensated for placental thinness by expanding the placental surface.

Professor Barker and his team also found that sudden cardiac death was strongly associated with low socio-economic status and with low education attainment. He suggests that 'poor educational results may be due to a poor cognitive ability or other issues such as the inability to concentrate or maintain attention. We suggest that the association we have found between sudden death and poor educational attainment results from impaired prenatal development of the autonomic nervous system. These findings build upon a body of research that has consistently reported associations between sudden cardiac death and low socio-economic status.'

In the study, a total of one hundred and eighty-seven men (2.7%) and forty seven women (0.7%) suffered from sudden unexplained cardiac death outside of the hospital. The rate of sudden cardiac death among men and women increased with placental thinness, with a hazard ratio of 1.47. The authors restricted their analysis to deaths that occurred outside of hospital and were certified as coronary heart disease, with men and women who had never been admitted to hospital with coronary heart disease.

Professor Barker and his team do acknowledge that there are some limitations to the study. The placental measurements were made during routing obstetric practice 70 years ago and the quality of these measurements was not routinely checked and neither were other clinical measurements, such as blood pressure. The mean placental weight in this study was also more than the median recorded in a recent series of deliveries in Europe.

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The above story is reprinted from materials provided by Oxford University Press, via EurekAlert!, a service of AAAS.

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Journal Reference:

  1. David JP Barker, Gail Larsen, Clive Osmond, Kent L Thornburg, Eero Kajantie, and Johan G Eriksson. The placental origins of sudden cardiac death. International Journal of Epidemiology, 2012; DOI: 10.1093/ije/dys116

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Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

20 Sep, 2012


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Humans were already recycling 13,000 years ago, burnt artifacts show

ScienceDaily (Sep. 20, 2012) — A study at the Universitat Rovira i Virgili and the Catalan Institute of Human Paleoecology and Social Evolution (IPHES) reveals that humans from the Upper Palaeolithic Age recycled their stone artefacts to be put to other uses. The study is based on burnt artefacts found in the Molí del Salt site in Tarragona, Spain.

The recycling of stone tools during Prehistoric times has hardly been dealt with due to the difficulties in verifying such practices in archaeological records. Nonetheless, it is possible to find some evidence, as demonstrated in a study published in the 'Journal of Archaeological Science'.

"In order to identify the recycling, it is necessary to differentiate the two stages of the manipulation sequence of an object: the moment before it is altered and the moment after. The two are separated by an interval in which the artefact has undergone some form of alteration. This is the first time a systematic study of this type has been performed," as explained to SINC by Manuel Vaquero, researcher at the Universitat Rovira i Virgili.

The archaeologists found a high percentage of burnt remains in the Molí del Salt site (Tarragona), which date back to the end of the Upper Palaeolithic Age some 13,000 years ago. The expert ensures that "we chose these burnt artefacts because they can tell us in a very simple way whether they have been modified after being exposed to fire."

The results indicate that the recycling of tools was normal during the Upper Palaeolithic Age. However, this practice is not documented in the same way as other types of artefacts. The use of recycled tools was more common for domestic activities and seems to be associated with immediate needs.

Recycling domestic tools

Recycling is linked to expedited behaviour, which means simply shaped and quickly available tools as and when the need arises. Tools used for hunting, like projectile points for instance, were almost never made from recycled artefacts. In contrast, double artefacts (those that combine two tools within the same item) were recycled more often.

"This indicates that a large part of these tools were not conceived from the outset as double artefacts but a single tool was made first and a second was added later when the artefact was recycled," outlines the researcher. The history of the artefacts and the sequence of changes that they have undergone over time are fundamental in understanding their final morphology.

According to Vaquero, "in terms of the objects, this is mostly important from a cultural value point of view, especially in periods like the Upper Palaeolithic Age, in which it is thought that the sharper the object the sharper the mind."

Sustainable practices with natural resources

Recycling could have been determinant in hunter-gatherer populations during the Palaeolithic Age if we consider the behaviour of current indigenous populations nowadays.

"It bears economic importance too, since it would have increased the availability of lithic resources, especially during times of scarcity. In addition, it is a relevant factor for interpreting sites because they become not just places to live but also places of resource provision," states the researcher.

Reusing resources meant that these humans did not have to move around to find raw materials to make their tools, a task that could have taken them far away from camp. "They would simply take an artefact abandoned by those groups who previously inhabited the site."

Vaquero and the team believe that this practice needs to be borne in mind when analysing the site. "Those populating these areas could have moved objects from where they were originally located. They even could have dug up or removed sediments in search of tools," highlights the researcher.

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The above story is reprinted from materials provided by Plataforma SINC, via AlphaGalileo.

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Journal Reference:

  1. Manuel Vaquero, Susana Alonso, Sergio García-Catalán, Angélica García-Hernández, Bruno Gómez de Soler, David Rettig, María Soto. Temporal nature and recycling of Upper Paleolithic artifacts: the burned tools from the Molí del Salt site (Vimbodí i Poblet, northeastern Spain). Journal of Archaeological Science, 2012; 39 (8): 2785 DOI: 10.1016/j.jas.2012.04.024

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20 Sep, 2012


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Invisible plastic particles in seawater damaging to sea animals

ScienceDaily (Sep. 20, 2012) — Plastic nanoparticles in seawater can have an adverse effect on sea organisms. Particles measuring about a thirty millionth of a millimetre, and therefore invisible to the naked eye, are responsible. Mussels that have been exposed to such particles eat less, and thus grow less well, according to research carried out by scientists and students at Wageningen University and IMARES, both part of Wageningen UR. They wrote about their research in the most recent issue of Environmental Toxicology and Chemistry.

The presence of 'plastic soup' in the oceans is regarded as a big problem. Tiny plastic particles enter the sea when plastic debris decomposes. Such particles are probably also released from cosmetics and from clothes in the wash, subsequently entering the sewage system and surface waters and eventually reaching the sea.

The EU and the Dutch government recognise the problem and the need to monitor the existence of plastics in the seas in order to learn more about present and future concentrations of plastic micro- and nanoparticles in marine environments. Very little is known about the effects plastic nanoparticles have on sea life. The effects now discovered do not yet prove that plastic in the North Sea is a big problem, but they do suggest that further research is extremely important, the researchers remark.

Professor Bart Koelmans' research team, from Wageningen University and IMARES, exposed mussels to various concentrations of nanoplastic in order to discover the concentration at which an effect was noticeable. The team also varied the quantity of algae -- the normal food source for mussels. By giving the plastic nanoparticles colour, and by measuring them using dynamic light scattering, it was possible to determine the particle concentration that exerted an effect. The researchers described in their publication that the extent to which the tiny plastic particles clump together is also extremely important for understanding particle uptake and the resulting effects in marine organisms. "It means that those effects are not easy to predict because the biological availability of the particles can differ enormously from one organism to another, and because variation in water quality also plays a role," says Prof. Koelmans.

Four research studies

This publication is the first of four by Wageningen University and IMARES into the effects of plastic in the North Sea. The other studies will be published in the near future. The first of these is research into the effect of plastic on lugworms, which lose weight due to uptake of plastic particles. The worms, as a result, take in more toxic substances such as polychlorinated biphenyls (PCBs), which bind to plastics.

The researchers believe this indicates the need for good research into other toxic substances that bind to plastic -- an additional consequence of the presence of microplastics. In order to analyse the interaction of plastic and other toxic substances in the food web, Koelmans' group has made a detailed computer model. This type of model is crucial for estimating the risks plastics impose in the sea. The last piece of research is into plastic debris in the stomachs of fish. An analysis of hundreds of fish has shown that 12% of them have debris in their stomachs. Around half of that debris is plastic.

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The above story is reprinted from materials provided by Wageningen University and Research Centre.

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Journal Reference:

  1. A. Wegner, E. Besseling, E.M. Foekema, P. Kamermans, A.A. Koelmans. Effects of nanopolystyrene on the feeding behavior of the blue mussel (Mytilus edulis L.). Environmental Toxicology and Chemistry, 2012; DOI: 10.1002/etc.1984

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20 Sep, 2012


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Invasive 'Rasberry Crazy Ant' in Texas now identified species

ScienceDaily (Sep. 19, 2012) — The Rasberry Crazy Ant is an invasive ant that was first noticed infesting areas around Houston, Texas ten years ago, but its species identity has remained undetermined until now.

In a paper published Sept. 19 in the open access journal PLOS ONE, a research team led by John LaPolla from Towson University in Maryland identifies the species as Nylanderia fulva. Identifying the species should help control this emerging pest, the authors write.

They also conclude that the species, whose common name comes from exterminator Tom Rasberry who first noticed the ants, is distributed more widely than previously thought and has likely invaded all Gulf Coast states.

"This study demonstrates the invaluable role that taxonomy, an often underappreciated discipline, plays in our understanding of emerging pests. Now that we know just what species the Rasberry Crazy Ant really is, we can better understand its biology to improve control of this invasive species," says LaPolla.

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Journal Reference:

  1. Dietrich Gotzek, Seán G. Brady, Robert J. Kallal, John S. LaPolla. The Importance of Using Multiple Approaches for Identifying Emerging Invasive Species: The Case of the Rasberry Crazy Ant in the United States. PLoS ONE, 2012; 7 (9): e45314 DOI: 10.1371/journal.pone.0045314

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20 Sep, 2012


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Obese children have less sensitive taste-buds than those of normal weight

ScienceDaily (Sep. 19, 2012) — Obese kids have less sensitive taste-buds than kids of normal weight, indicates research published online in the Archives of Disease in Childhood.

This blunted ability to distinguish all five tastes of bitter, sweet, salty, sour, and umami (savoury) may prompt them to eat larger quantities of food in a bid to register the same taste sensation, suggest the authors.

They base their findings on 94 normal weight and 99 obese children aged between 6 and 18, who were in good health and not taking any medications known to affect taste and smell.

The taste sensitivity of every child was tested using 22 "taste strips" placed on the tongue, to include each of the five taste sensations, at four different levels of intensity, plus two blank strips.

Each child was asked to refrain from eating or drinking anything other than water and not to chew gum for at least an hour before they took the two tests, which involved identifying the different tastes and their intensity.

The sum of all five taste sensations at the four different intensities allowed for a maximum score of 20, with scores ranging from two to 19.

Girls and older children were better at picking out the right tastes.

Overall, the children were best able to differentiate between sweet and salty, but found it hardest to distinguish between salty and sour, and between salty and umami.

And obese children found it significantly more difficult to identify the different taste sensations, scoring an average of 12.6 compared with an average of just over 14 clocked up by children of normal weight.

Obese children were significantly less likely to identify the individual taste sensations correctly, particularly salty, umami, and bitter.

And while both obese and normal weight children correctly identified all the differing levels of sweetness, obese kids rated three out of the four intensity levels lower than kids of normal weight.

Similarly, children of normal weight were better able to distinguish the different taste sensations, the older they were, but this trend was not seen among the obese children.

Exactly why people have differing taste perceptions is unclear, but genes, hormones, acculturation and exposure to different tastes early in life are all thought to play a part, say the authors.

But previous research indicates that heightened sensitivity to different taste sensations may help to reduce the amount of food eaten as less is required to get the same "taste hit."

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The above story is reprinted from materials provided by BMJ-British Medical Journal.

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  1. Johanna Overberg, Thomas Hummel, Heiko Krude, Susanna Wiegand. Differences in taste sensitivity between obese and non-obese children and adolescents. Archives of Disease in Childhood, 2012; DOI: 10.1136/archdischild-2011-301189

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20 Sep, 2012


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NASA Mars rover targets unusual rock enroute to first destination

Written By Unknown on Rabu, 19 September 2012 | 17.47

ScienceDaily (Sep. 19, 2012) — NASA's Mars rover Curiosity has driven up to a football-size rock that will be the first for the rover's arm to examine.

Curiosity is about 8 feet (2.5 meters) from the rock. It lies about halfway from the rover's landing site, Bradbury Landing, to a location called Glenelg. In coming days, the team plans to touch the rock with a spectrometer to determine its elemental composition and use an arm-mounted camera to take close-up photographs.

Both the arm-mounted Alpha Particle X-Ray Spectrometer and the mast-mounted, laser-zapping Chemistry and Camera Instrument will be used for identifying elements in the rock. This will allow cross-checking of the two instruments.

The rock has been named "Jake Matijevic." Jacob Matijevic (mah-TEE-uh-vik) was the surface operations systems chief engineer for Mars Science Laboratory and the project's Curiosity rover. He passed away Aug. 20, at age 64. Matijevic also was a leading engineer for all of the previous NASA Mars rovers: Sojourner, Spirit and Opportunity.

Curiosity now has driven six days in a row. Daily distances range from 72 feet to 121 feet (22 meters to 37 meters).

"This robot was built to rove, and the team is really getting a good rhythm of driving day after day when that's the priority," said Mars Science Laboratory Project Manager Richard Cook of NASA's Jet Propulsion Laboratory in Pasadena, Calif.

The team plans to choose a rock in the Glenelg area for the rover's first use of its capability to analyze powder drilled from interiors of rocks. Three types of terrain intersect in the Glenelg area -- one lighter-toned and another more cratered than the terrain Curiosity currently is crossing. The light-toned area is of special interest because it retains daytime heat long into the night, suggesting an unusual composition.

"As we're getting closer to the light-toned area, we see thin, dark bands of unknown origin," said Mars Science Laboratory Project Scientist John Grotzinger of the California Institute of Technology, Pasadena. "The smaller-scale diversity is becoming more evident as we get closer, providing more potential targets for investigation."

Researchers are using Curiosity's Mast Camera (Mastcam) to find potential targets on the ground. Recent new images from the rover's camera reveal dark streaks on rocks in the Glenelg area that have increased researchers' interest in the area. In addition to taking ground images, the camera also has been busy looking upward.

On two recent days, Curiosity pointed the Mastcam at the sun and recorded images of Mars' two moons, Phobos and Deimos, passing in front of the sun from the rover's point of view. Results of these transit observations are part of a long-term study of changes in the moons' orbits. NASA's twin Mars Exploration Rovers, Spirit and Opportunity, which arrived at Mars in 2004, also have observed solar transits by Mars' moons. Opportunity is doing so again this week.

"Phobos is in an orbit very slowly getting closer to Mars, and Deimos is in an orbit very slowly getting farther from Mars," said Curiosity's science team co-investigator Mark Lemmon of Texas A&M University, College Station. "These observations help us reduce uncertainty in calculations of the changes."

In Curiosity's observations of Phobos this week, the time when the edge of the moon began overlapping the disc of the sun was predictable to within a few seconds. Uncertainty in timing is because Mars' interior structure isn't fully understood.

Phobos causes small changes to the shape of Mars in the same way Earth's moon raises tides. The changes to Mars' shape depend on the Martian interior which, in turn, cause Phobos' orbit to decay. Timing the orbital change more precisely provides information about Mars' interior structure.

During Curiosity's two-year prime mission, researchers will use the rover's 10 science instruments to assess whether the selected field site inside Gale Crater ever has offered environmental conditions favorable for microbial life.

For more about Curiosity, visit: http://www.nasa.gov/msl and http://mars.jpl.nasa.gov/msl. You can follow the mission on Facebook and Twitter at: http://www.facebook.com/marscuriosity and http://www.twitter.com/marscuriosity.

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20 Sep, 2012


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Promise of cell therapy for bowel disease

ScienceDaily (Sep. 19, 2012) — New research shows that a special population of stem cells found in cord blood has the innate ability to migrate to the intestine and contribute to the cell population there, suggesting the cells' potential to treat inflammatory bowel disease (IBD).

"These cells are involved in the formation of blood vessels and may prove to be a tool for improving the vessel abnormalities found in IBD," said lead author Graca Almeida-Porada, M.D., Ph.D., a professor at Wake Forest Baptist Medical Center's Institute for Regenerative Medicine. The research is published in the current print issue of the journal Hepatology.

Up to 1 million Americans have IBD, which is characterized by frequent diarrhea and abdominal pain. IBD actually refers to two conditions -- ulcerative colitis and Crohn's disease -- in which the intestines become red and swollen and develop ulcers. With IBD, blood vessels in the intestine leak and contribute to inflammation.

While there is currently no cure for IBD, there are drug therapies aimed at reducing inflammation and preventing the immune response. However, these therapies aren't always effective. The long-term aim of the research is to develop an injectable cell therapy to induce tissue recovery.

The work, performed while Almeida-Porada was at the University of Nevada, also involved colleagues from Indiana University School of Medicine. The researchers studied a special population of cells, known as endothelial colony-forming cells, found in cord blood, bone marrow and circulating blood. The finding in 1997 that the cells can contribute to blood vessel formation in adults, not just embryos, initiated the notion of using them for therapy. Studies in humans have validated the ability of these cells to improve reduced blood flow to the limbs and to treat heart diseases.

However, there have been few studies to explore the inherent biologic ability of these cells to home to different organs and contribute to tissue-specific cell populations. Evaluating their potential to migrate to the intestine was an obvious choice, said Almeida-Porada, because dysfunctional blood vessels are a hallmark of IBD. Not only are circulating levels of vessel-forming cells reduced in patients with IBD, but a key factor in IBD progression is the development of abnormal or immature blood vessels, which leads to chronic inflammation.

The cells were injected into fetal sheep at 59 to 65 days gestation. About 11 weeks later, intestinal tissue was analyzed to detect the presence of the human cells. The researchers found that the human cells had migrated to the intestine and contributed significantly to the cell population there.

"This study shows that the cells can migrate to and survive in a healthy intestine and have the potential to support vascular health," said Almeida-Porada. "Our next step will be to determine whether the cells can survive in the 'war' environment of an inflamed intestine."

The researchers also evaluated the ability of the cells to home to the liver. Smaller numbers of cells reached the liver than the intestine, suggesting that new strategies would be needed to enhance the therapeutic potential for this organ.

The research was supported by the National Heart, Lung, and Blood Institute grants HL097623 and HL073737.

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The above story is reprinted from materials provided by Wake Forest Baptist Medical Center, via Newswise.

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Journal Reference:

  1. Joshua A. Wood, Evan Colletti, Laura E. Mead, David Ingram, Christopher D. Porada, Esmail D. Zanjani, Mervin C. Yoder, Graça Almeida-Porada. Distinct contribution of human cord blood-derived endothelial colony forming cells to liver and gut in a fetal sheep model. Hepatology, 2012; 56 (3): 1086 DOI: 10.1002/hep.25753

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20 Sep, 2012


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Blind people develop accurate mental map by playing 'video' game

ScienceDaily (Sep. 19, 2012) — Researchers have developed a new "video" game for blind people that can help them learn about a new space using only audio cues, as reported Sept. 19 in the open access journal PLOS ONE.

The system, developed by a team led by Lotfi Merabet of Harvard Medical School and Jaime Sánchez of the University of Chile, is called the Audiobased Environment Simulator and uses only audio-based cues to allow blind users to learn about the layout of a previously unfamiliar building.

After playing the game, participants were better able to navigate a real-world version of the space explored in the virtual reality environment, confirming that the spatial information learned in the game was accurate and transferrable.

"Learning through such interactive games represents an innovative and motivating way to improve crucial skills that allow blind individuals to remain functionally independent," says Merabet.

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Journal Reference:

  1. Lotfi B. Merabet, Erin C. Connors, Mark A. Halko, Jaime Sánchez. Teaching the Blind to Find Their Way by Playing Video Games. PLoS ONE, 2012; 7 (9): e44958 DOI: 10.1371/journal.pone.0044958

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20 Sep, 2012


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People change moral position without even realizing it

ScienceDaily (Sep. 19, 2012) — Shortly after expressing a moral view about a difficult topic, people may easily endorse the opposite view and remain blind to the psychological mismatch, according to research published Sept. 19 in the open access journal PLOS ONE.

In the study, led by Lars Hall of Lund University, Sweden, participants were presented with a survey about moral issues, including foundational principles and current hot topics with moral implications. To complete the survey they had to flip over the first page of questions, which was displayed on a clipboard, and this is where the researchers implemented a design usually used in performance magic: the back of the clipboard had a patch of glue that caught the top layer of the questions, so when the page was flipped back over, an opposite version of the original questions was revealed but the answers remained unchanged. In other words, the participants' responses were opposite to their originally declared positions (For a video illustration of the experiment, see http://www.lucs.lu.se/cbq/).

The researchers then discussed the participants' answers with them, and found that many participants supported their reported answers, even though the responses were opposite to what the individual had originally intended to express. The authors write that "participants often constructed coherent and unequivocal arguments supporting the opposite of their original position," suggesting "a dramatic potential for flexibility in our moral attitudes."

Commenting on their results, Lars Hall says, "It could have significant impact on research that uses self-reported questionnaires. Either we would have to conclude that many participants hold no real attitudes about the topics we investigate, or that standard survey scales fail to capture the complexity of the attitudes people actually hold."

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Journal Reference:

  1. Lars Hall, Petter Johansson, Thomas Strandberg. Lifting the Veil of Morality: Choice Blindness and Attitude Reversals on a Self-Transforming Survey. PLoS ONE, 2012; 7 (9): e45457 DOI: 10.1371/journal.pone.0045457

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20 Sep, 2012


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DNA barcoding can ID natural health products

ScienceDaily (Sep. 19, 2012) — DNA barcoding developed by University of Guelph researchers has proven up to 88 per cent effective in authenticating natural health products, according to a new U of G study.

The study appears in the latest issue of Food Research International. It's a crucial finding because the health product industry is under-regulated worldwide and mislabelling poses economic, health, legal and environmental implications, says study author Mehrdad Hajibabaei.

"Currently there is no other broadly applicable tool that can identify the species used in both animal and plant natural health products as rapidly and cost-effectively," said Hajibabaei, a U of G integrative biology professor and director of technology development for the Guelph-based Biodiversity Institute of Ontario (BIO).

Up to about 80 per cent of people in developed countries use natural health products, including vitamins, minerals and herbal remedies. In Canada, these products have been regulated since 2004. But regulators face a backlog of licence applications, and thousands of products on the market lack a full product licence. In the U.S. and the U.K., regulatory problems involving natural health products have affected consistency and safety.

Authenticating natural product capsules or tablets -- containing dried fragments rather than whole specimens -- poses challenges.

DNA barcoding allows scientists to use short standardized regions of genetic material to identify species and compare them to reference genetic sequences, said Hajibabaei.

The technique works for all life stages and even for fragments of organisms, allowing scientists to ID even dried contents of a small pill.

"DNA barcoding provides a simple and efficient method for accurate identification and can play a key role in developing a more robust protocol for their regulation," Hajibabaei said.

For the study, researchers tested 95 plant and animal products bought in Toronto and New York City. Samples included capsules, tablets, roots, extracts, teas and shredded products. The researchers also sampled for products containing widely used shark tissue or ginseng.

Fully 81 per cent of natural health products made from animals correctly matched their commercial label. The rest contained everything from cheaper alternatives to fragments of protected species. One product labelled as tiger shark fins actually contained a catfish species.

Several of the identified shark species are on the "red list" of the International Union for the Conservation of Nature.

Half of the plant products labelled as Korean ginseng -- which is more expensive and is sold for different medicinal benefits than other types -- were really American ginseng.

Besides Hajibabaei, the study was headed by Lauren Wallace, a former President's Scholar at U of G and now a doctoral student at McMaster University. Wallace received a summer research fellowship from the Ontario Genomics Institute in 2010 to work on the BIO project.

Other researchers were Stephanie Boilard, now a technician in Hajibabaei's lab; graduate students Shannon Eagle and Jennifer Spall; and post-doc Shadi Shokralla.

Three of the researchers were using DNA barcoding for the first time. "Ultimately, the study showcases the utility of DNA barcodes for use in the real world," Hajibabaei said.

The BIO is a hub for barcoding research worldwide and leads the International Barcode of Life (www.ibol.org) project to develop a DNA barcode reference library. Another project based at the institute is Biomonitoring 2.0 (www.biomonitoring2.org), which uses barcoding and DNA sequencing for large-scale environmental assessment.

This research has been funded by the federal government through Genome Canada and the Ontario Genomics Institute.

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Journal Reference:

  1. Lauren J. Wallace, Stephanie M.A.L. Boilard, Shannon H.C. Eagle, Jennifer L. Spall, Shadi Shokralla, Mehrdad Hajibabaei. DNA barcodes for everyday life: Routine authentication of Natural Health Products. Food Research International, 2012; DOI: 10.1016/j.foodres.2012.07.048

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20 Sep, 2012


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Climate change to fuel northern spread of avian malaria: Malaria already found in birds in Alaska

ScienceDaily (Sep. 19, 2012) — Malaria has been found in birds in parts of Alaska, and global climate change will drive it even farther north, according to a new study published September 19 in the journal PLoS ONE.

The spread could prove devastating to arctic bird species that have never encountered the disease and thus have no resistance to it, said San Francisco State University Associate Professor of Biology Ravinder Sehgal, one of the study's co-authors. It may also help scientists understand the effects of climate change on the spread of human malaria, which is caused by a similar parasite.

Researchers examined blood samples from birds collected at four sites of varying latitude, with Anchorage as a southern point, Denali and Fairbanks as middle points and Coldfoot as a northern point, roughly 600 miles north of Anchorage. They found infected birds in Anchorage and Fairbanks but not in Coldfoot.

Using satellite imagery and other data, researchers were able to predict how environments will change due to global warming -- and where malaria parasites will be able to survive in the future. They found that by 2080, the disease will have spread north to Coldfoot and beyond.

"Right now, there's no avian malaria above latitude 64 degrees, but in the future, with global warming, that will certainly change," Sehgal said. The northerly spread is alarming, he added, because there are species in the North American arctic that have never been exposed to the disease and may be highly susceptible to it.

"For example, penguins in zoos die when they get malaria, because far southern birds have not been exposed to malaria and thus have not developed any resistance to it," he said. "There are birds in the north, such as snowy owls or gyrfalcons, that could experience the same thing."

The study's lead author is Claire Loiseau, a former postdoctoral fellow in Sehgal's laboratory at SF State. Ryan Harrigan, a postdoctoral scholar at the University of California, Los Angeles, provided data modeling for the project. The research was funded by grants from the AXA Foundation and National Geographic.

Researchers are still unsure how the disease is being spread in Alaska and are currently collecting additional data to determine which mosquito species are transmitting the Plasmodium parasites that cause malaria.

The data may also indicate if and how malaria in humans will spread northward. Modern medicine makes it difficult to track the natural spread of the disease, Sehgal said, but monitoring birds may provide clues as to how global climate change may effect the spread of human malaria.

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Journal Reference:

  1. Claire Loiseau, Ryan J. Harrigan, Anthony J. Cornel, Sue L. Guers, Molly Dodge, Timothy Marzec, Jenny S. Carlson, Bruce Seppi, Ravinder N. M. Sehgal. First Evidence and Predictions of Plasmodium Transmission in Alaskan Bird Populations. PLoS ONE, 2012; 7 (9): e44729 DOI: 10.1371/journal.pone.0044729

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Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

20 Sep, 2012


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Arctic sea ice hits smallest extent in satellite era

ScienceDaily (Sep. 19, 2012) — The frozen cap of the Arctic Ocean appears to have reached its annual summertime minimum extent and broken a new record low on Sept. 16, the National Snow and Ice Data Center (NSIDC) has reported. Analysis of satellite data by NASA and the NASA-supported NSIDC at the University of Colorado in Boulder showed that the sea ice extent shrunk to 1.32 million square miles (3.41 million square kilometers).

The new record minimum measures almost 300,000 square miles less than the previous lowest extent in the satellite record, set in mid-September 2007, of 1.61 million square miles (4.17 million square kilometers). For comparison, the state of Texas measures around 268,600 square miles.

NSIDC cautioned that, although Sept. 16 seems to be the annual minimum, there's still time for winds to change and compact the ice floes, potentially reducing the sea ice extent further. NASA and NSIDC will release a complete analysis of the 2012 melt season next month, once all data for September are available.

Arctic sea ice cover naturally grows during the dark Arctic winters and retreats when the sun re-appears in the spring. But the sea ice minimum summertime extent, which is normally reached in September, has been decreasing over the last three decades as Arctic ocean and air temperatures have increased. This year's minimum extent is approximately half the size of the average extent from 1979 to 2000. This year's minimum extent also marks the first time Arctic sea ice has dipped below 4 million square kilometers.

"Climate models have predicted a retreat of the Arctic sea ice; but the actual retreat has proven to be much more rapid than the predictions," said Claire Parkinson, a climate scientist at NASA Goddard Space Flight Center, Greenbelt, Md. "There continues to be considerable inter-annual variability in the sea ice cover, but the long-term retreat is quite apparent."

The thickness of the ice cover is also in decline.

"The core of the ice cap is the perennial ice, which normally survived the summer because it was so thick," said Joey Comiso, senior scientist with NASA Goddard. "But because it's been thinning year after year, it has now become vulnerable to melt."

The disappearing older ice gets replaced in winter with thinner seasonal ice that usually melts completely in the summer.

This year, a powerful cyclone formed off the coast of Alaska and moved on Aug. 5 to the center of the Arctic Ocean, where it churned the weakened ice cover for several days. The storm cut off a large section of sea ice north of the Chukchi Sea and pushed it south to warmer waters that made it melt entirely. It also broke vast extensions of ice into smaller pieces more likely to melt.

"The storm definitely seems to have played a role in this year's unusually large retreat of the ice," Parkinson said. "But that exact same storm, had it occurred decades ago when the ice was thicker and more extensive, likely wouldn't have had as prominent an impact, because the ice wasn't as vulnerable then as it is now."

NASA scientists derive 2012 sea ice concentration data from microwave instruments aboard Defense Meteorological Satellite Program satellites. The wind data in the visualization is from the National Centers for Environmental Prediction.

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20 Sep, 2012


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Ancient tooth may provide evidence of early human dentistry

ScienceDaily (Sep. 19, 2012) — Researchers may have uncovered new evidence of ancient dentistry in the form of a 6,500-year-old human jaw bone with a tooth showing traces of beeswax filling, as reported Sept. 19 in the open access journal PLOS ONE.

The researchers, led by Federico Bernardini and Claudio Tuniz of the Abdus Salam International Centre for Theoretical Physics in Italy in cooperation with Sincrotrone Trieste and other institutions, write that the beeswax was applied around the time of the individual's death, but cannot confirm whether it was shortly before or after. If it was before death, however, they write that it was likely intended to reduce pain and sensitivity from a vertical crack in the enamel and dentin layers of the tooth.

According to Tuniz, the severe wear of the tooth "is probably also due to its use in non-alimentary activities, possibly such as weaving, generally performed by Neolithic females."

Evidence of prehistoric dentistry is sparse, so this new specimen, found in Slovenia near Trieste, may help provide insight into early dental practices.

"This finding is perhaps the most ancient evidence of pre-historic dentistry in Europe and the earliest known direct example of therapeutic-palliative dental filling so far," says Bernardini.

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Journal Reference:

  1. Federico Bernardini, Claudio Tuniz, Alfredo Coppa, Lucia Mancini, Diego Dreossi, Diane Eichert, Gianluca Turco, Matteo Biasotto, Filippo Terrasi, Nicola De Cesare, Quan Hua, Vladimir Levchenko. Beeswax as Dental Filling on a Neolithic Human Tooth. PLoS ONE, 2012; 7 (9): e44904 DOI: 10.1371/journal.pone.0044904

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20 Sep, 2012


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Misinformation: Why it sticks and how to fix it

ScienceDaily (Sep. 19, 2012) — Childhood vaccines do not cause autism. Barack Obama was born in the United States. Global warming is confirmed by science. And yet, many people believe claims to the contrary.

Why does that kind of misinformation stick? A new report published in Psychological Science in the Public Interest, a journal of the Association for Psychological Science, explores this phenomenon. Psychological scientist Stephan Lewandowsky of the University of Western Australia and colleagues highlight the cognitive factors that make certain pieces of misinformation so "sticky" and identify some techniques that may be effective in debunking or counteracting erroneous beliefs.

The main reason that misinformation is sticky, according to the researchers, is that rejecting information actually requires cognitive effort. Weighing the plausibility and the source of a message is cognitively more difficult than simply accepting that the message is true -- it requires additional motivational and cognitive resources. If the topic isn't very important to you or you have other things on your mind, misinformation is more likely to take hold.

And when we do take the time to thoughtfully evaluate incoming information, there are only a few features that we are likely to pay attention to: Does the information fit with other things I believe in? Does it make a coherent story with what I already know? Does it come from a credible source? Do others believe it?

Misinformation is especially sticky when it conforms to our preexisting political, religious, or social point of view. Because of this, ideology and personal worldviews can be especially difficult obstacles to overcome.

Even worse, efforts to retract misinformation often backfire, paradoxically amplifying the effect of the erroneous belief.

"This persistence of misinformation has fairly alarming implications in a democracy because people may base decisions on information that, at some level, they know to be false," says Lewandowsky.

"At an individual level, misinformation about health issues -- for example, unwarranted fears regarding vaccinations or unwarranted trust in alternative medicine -- can do a lot of damage. At a societal level, persistent misinformation about political issues (e.g., Obama's health care reform) can create considerable harm. On a global scale, misinformation about climate change is currently delaying mitigative action."

Though misinformation may be difficult to correct, all is not lost. According to Lewandowsky, "psychological science has the potential to counteract all those harms by educating people and communicators about the power of misinformation and how to meet it."

In their report, Lewandowsky and colleagues offer some strategies for setting the record straight.

  • Provide people with a narrative that replaces the gap left by false information
  • Focus on the facts you want to highlight, rather than the myths
  • Make sure that the information you want people to take away is simple and brief
  • Consider your audience and the beliefs they are likely to hold
  • Strengthen your message through repetition

Research has shown that attempts at "debiasing" can be effective in the real world when based on these evidence-based strategies.

The report, "Misinformation and its Correction: Continued Influence and Successful Debiasing," is published in the September issue of Psychological Science in the Public Interest and is written by Stephan Lewandowsky and Ullrich Ecker of the University of Western Australia, Colleen Seifert and Norbert Schwarz of the University of Michigan, and John Cook of the University of Queensland and the University of Western Australia.

The report also features a commentary written by Edward Maibach of George Mason University.

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Journal Reference:

  1. S. Lewandowsky, U. K. H. Ecker, C. M. Seifert, N. Schwarz, J. Cook. Misinformation and Its Correction: Continued Influence and Successful Debiasing. Psychological Science in the Public Interest, 2012; 13 (3): 106 DOI: 10.1177/1529100612451018

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20 Sep, 2012


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Dyslexia cause may be different than previously thought

ScienceDaily (Sep. 19, 2012) — Dyslexia may result from impairment of a different linguistic system than previously thought, according to research published Sep. 19 in the open access journal PLOS ONE.

Speech perception engages at least two linguistic systems: the phonetic system, which extracts discrete sound units from acoustic input, and the phonological system, which combines these units to form individual words. Previously, researchers generally believed that dyslexia was caused by phonological impairment, but results from the current study, led by Iris Berent of Northeastern University in Boston, suggest that the phonetic system may actually be the cause.

"Our findings confirm that dyslexia indeed compromises the language system, but the locus of the deficit is in the phonetic, not the phonological system, as had been previously assumed," says Berent.

In the study, Hebrew-speaking college students had difficulty discriminating between similar speech sounds, but had no problem tracking abstract phonological patterns, even for novel words, suggesting that the phonological system is intact but the phonetic system is compromised.

"Our research demonstrates that a closer analysis of the language system can radically alter our understanding of the disorder, and ultimately, its treatment," says Berent.

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Journal Reference:

  1. Iris Berent, Vered Vaknin-Nusbaum, Evan Balaban, Albert M. Galaburda. Dyslexia Impairs Speech Recognition but Can Spare Phonological Competence. PLoS ONE, 2012; 7 (9): e44875 DOI: 10.1371/journal.pone.0044875

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

20 Sep, 2012


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Climate scientists put predictions to the test

ScienceDaily (Sep. 19, 2012) — Climate-prediction models show skills in forecasting climate trends over time spans of greater than 30 years and at the geographical scale of continents, but they deteriorate when applied to shorter time frames and smaller geographical regions, a new study has found.

Published in the Journal of Geophysical Research-Atmospheres, the study is one of the first to systematically address a longstanding, fundamental question asked not only by climate scientists and weather forecasters, but the public as well: How good are Earth system models at predicting the surface air temperature trend at different geographical and time scales?

Xubin Zeng, a professor in the University of Arizona department of atmospheric sciences who leads a research group evaluating and developing climate models, said the goal of the study was to bridge the communities of climate scientists and weather forecasters, who sometimes disagree with respect to climate change.

According to Zeng, who directs the UA Climate Dynamics and Hydrometeorology Center, the weather forecasting community has demonstrated skill and progress in predicting the weather up to about two weeks into the future, whereas the track record has remained less clear in the climate science community tasked with identifying long-term trends for the global climate.

"Without such a track record, how can the community trust the climate projections we make for the future?" said Zeng, who serves on the Board on Atmospheric Sciences and Climate of the National Academies and the Executive Committee of the American Meteorological Society. "Our results show that actually both sides' arguments are valid to a certain degree."

"Climate scientists are correct because we do show that on the continental scale, and for time scales of three decades or more, climate models indeed show predictive skills. But when it comes to predicting the climate for a certain area over the next 10 or 20 years, our models can't do it."

To test how accurately various computer-based climate prediction models can turn data into predictions, Zeng's group used the "hindcast" approach.

"Ideally, you would use the models to make predictions now, and then come back in say, 40 years and see how the predictions compare to the actual climate at that time," said Zeng. "But obviously we can't wait that long. Policymakers need information to make decisions now, which in turn will affect the climate 40 years from now."

Zeng's group evaluated seven computer simulation models used to compile the reports that the Intergovernmental Panel on Climate Change, or IPCC, issues every six years. The researchers fed them historical climate records and compared their results to the actual climate change observed between then and now.

"We wanted to know at what scales are the climate models the IPCC uses reliable," said Koichi Sakaguchi, a doctoral student in Zeng's group who led the study. "These models considered the interactions between the Earth's surface and atmosphere in both hemispheres, across all continents and oceans and how they are coupled."

Zeng said the study should help the community establish a track record whose accuracy in predicting future climate trends can be assessed as more comprehensive climate data become available.

"Our goal was to provide climate modeling centers across the world with a baseline they can use every year as they go forward," Zeng added. "It is important to keep in mind that we talk about climate hindcast starting from 1880. Today, we have much more observational data. If you start your prediction from today for the next 30 years, you might have a higher prediction skill, even though that hasn't been proven yet."

The skill of a climate model depends on three criteria at a minimum, Zeng explained. The model has to use reliable data, its prediction must be better than a prediction based on chance, and its prediction must be closer to reality than a prediction that only considers the internal climate variability of the Earth system and ignores processes such as variations in solar activity, volcanic eruptions, greenhouse gas emissions from fossil fuel burning and land-use change, for example urbanization and deforestation.

"If a model doesn't meet those three criteria, it can still predict something but it cannot claim to have skill," Zeng said.

According to Zeng, global temperatures have increased in the past century by about 1.4 degrees Fahrenheit or 0.8 degrees Celsius on average. Barring any efforts to curb global warming from greenhouse gas emissions, the temperatures could further increase by about 4.5 degrees Fahrenheit (2.5 degrees Celsius) or more by the end of the 21st century based on these climate models.

"The scientific community is pushing policymakers to avoid the increase of temperatures by more than 2 degrees Celsius because we feel that once this threshold is crossed, global warming could be damaging to many regions," he said.

Zeng said that climate models represent the current understanding of the factors influencing climate, and then translate those factors into computer code and integrate their interactions into the future.

"The models include most of the things we know," he explained, "such as wind, solar radiation, turbulence mixing in the atmosphere, clouds, precipitation and aerosols, which are tiny particles suspended in the air, surface moisture and ocean currents."

Zeng described how the group did the analysis: "With any given model, we evaluated climate predictions from 1900 into the future -- 10 years, 20 years, 30 years, 40 years, 50 years. Then we did the same starting in 1901, then 1902 and so forth, and applied statistics to the results."

Climate models divide the Earth into grid boxes whose size determines its spatial resolution. According to Zeng, state of the art is about one degree, equaling about 60 miles (100 kilometers).

"There has to be a simplification because if you look outside the window, you realize you don't typically have a cloud cover that measures 60 miles by 60 miles. The models cannot reflect that kind of resolution. That's why we have all those uncertainties in climate prediction."

"Our analysis confirmed what we expected from last IPCC report in 2007," said Sakaguchi. "Those climate models are believed to be of good skill on large scales, for example predicting temperature trends over several decades, and we confirmed that by showing that the models work well for time spans longer than 30 years and across geographical scales spanning 30 degrees or more."

The scientists pointed out that although the IPCC issues a new report every six years, they didn't see much change with regard to the prediction skill of the different models.

"The IPCC process is driven by international agreements and politics," Zeng said. "But in science, we are not expected to make major progress in just six years. We have made a lot of progress in understanding certain processes, for example airborne dust and other small particles emitted from surface, either through human activity or through natural sources into the air. But climate and the Earth system still are extremely complex. Better understanding doesn't necessarily translate into better skill in a short time."

"Once you go into details, you realize that for some decades, models are doing a much better job than for some other decades. That is because our models are only as good as our understanding of the natural processes, and there is a lot we don't understand."

Michael Brunke, a graduate student in Zeng's group who focused on ocean-atmosphere interactions, co-authored the study, which is titled "The Hindcast Skill of the CMIP Ensembles for the Surface Air Temperature Trend."

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The above story is reprinted from materials provided by University of Arizona, via EurekAlert!, a service of AAAS.

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Journal Reference:

  1. Koichi Sakaguchi, Xubin Zeng, Michael A. Brunke. The hindcast skill of the CMIP ensembles for the surface air temperature trend. Journal of Geophysical Research, 2012; 117 (D16) DOI: 10.1029/2012JD017765

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

20 Sep, 2012


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Odorant shape and vibration likely lead to olfaction satisfaction

ScienceDaily (Sep. 19, 2012) — A new study of the sense of smell lends support to a controversial theory of olfaction: Our noses can distinguish both the shape and the vibrational characteristics of odorant molecules.

The study, in the journal Physical Chemistry Chemical Physics, demonstrates the feasibility of the theory -- first proposed decades ago -- that the vibration of an odorant molecule's chemical bonds -- the wagging, stretching and rocking of the links between atoms -- contributes to our ability to distinguish one smelly thing from another.

"The theory goes that when the right odorant binds to its receptor, the odorant's molecular vibration allows electrons to transfer from one part of the receptor to another," said University of Illinois physics and Beckman Institute professor Klaus Schulten, who conducted the analysis with postdoctoral researcher Ilia Solov'yov and graduate student Po-Yao Chang. "This electron transfer appears to fine-tune the signal the receptor receives."

Many who study olfaction maintain that odorant receptors recognize only an odorant's shape and surface characteristics. They dismiss the idea that molecular vibration has anything to do with it, Schulten said. Likewise, some proponents of the vibrational theory think that molecular vibration only, and not shape, guides the sense of smell. Schulten and his colleagues belong to a "third camp" that sees evidence for both, he said.

The vibrational theory of olfaction is supported by studies showing that insects, humans and other animals can tell the difference between two versions of the same odorant molecule -- a normal one and an identical one with deuterium atoms substituted for each of the hydrogens. The deuterated and normal versions of the odorant have the same shape and surface characteristics, and yet humans and other animals can smell the difference, Schulten said.

"The question then is of course, for scientists, how does this happen?" he said.

To answer this question, Schulten turned to the work of a former colleague at Illinois, Rudolph Marcus, a chemist (now at the California Institute of Technology) who received the Nobel Prize in Chemistry in 1992 for his insights into electron transfer, one of the most basic forms of a chemical reaction.

"Marcus realized that when electrons are being exchanged between molecules the process is coupled to the vibrations of the molecules involved," Schulten said. Marcus focused primarily on the low-frequency "rumblings" that occur as a result of molecular vibration in large molecules, Schulten said.

Odorant molecules are generally quite small, however, with a lot of high-frequency, high-energy vibrations, Schulten said. Some scientists have theorized that these high-frequency vibrations can, when an odorant binds to the right receptor, enhance the likelihood that an electron will transfer from one part of the receptor to another, sending an electrical signal that contributes to the detection of that odor.

Prior to the new study, no one had analyzed the energetics of the system to see if the vibrations of the odorant molecules -- in the context of all the background vibrations that are part of the system -- could actually promote electron transfer within the receptor. Schulten and his colleagues are the first to conduct such an analysis, he said.

"You can actually carry out quantum chemical calculations that determine very precisely the vibration of the molecule as well as the ability to couple it to electron transfer," Schulten said. The calculations indicate that such an interaction is energetically feasible, he said.

Odorant receptors are embedded in membranes and so are more difficult to study than other proteins. But previous research indicates that some receptors are metalloproteins, and "the metals in the proteins are predesigned to transfer electrons," Schulten said. "We also see that there are other amino acid side groups that can accept an electron, so the electron can be transferred through the protein."

Like others before them, Schulten and his colleagues suggest that the odorant receptor contains both an electron donor and an electron acceptor, but that electron transfer occurs only when a specific odorant is bound to the receptor. The new calculations offer the first quantitative evidence that the odorant can in fact promote electron transfer.

Those who suggested that molecular vibration played a role in odorant recognition in previous studies "didn't know about Marcus' theory and they didn't do quantum chemical calculations," Schulten said. "They argued very much on principle (that it was possible). So we are saying now, yes, it is really possible even when you do the most complete and reliable calculations."

Video: http://www.youtube.com/watch?v=Oe5PW2KqImI

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The above story is reprinted from materials provided by University of Illinois at Urbana-Champaign.

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Journal Reference:

  1. Ilia A. Solov'yov, Po-Yao Chang, Klaus Schulten. Vibrationally assisted electron transfer mechanism of olfaction: myth or reality? Physical Chemistry Chemical Physics, 2012; DOI: 10.1039/C2CP41436H

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

20 Sep, 2012


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Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/RJsO4o1Hpkc/120919135322.htm
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